Polyacetylenes – bioactive compounds with potential
Polyacetylenes are an exciting class of organic compounds characterised by multiple C≡C triple bonds. Although they appear unstable in their pure form, they exhibit remarkable stability when bound in plants, fungi or marine organisms. It is precisely this balance of reactivity and stability that makes these polymers highly interesting molecules for cosmetic research and application.
Polyacetylenes – occurrence and properties
They occur in numerous plant families, especially in the Apiaceae (umbellifers) and in carrot roots. There, they are not only responsible for the slightly bitter taste, but also perform an important protective function due to their antimicrobial properties.
Ginseng is also rich in polyacetylenes. In addition to the well-known ginsenosides, compounds such as panaxynol, panaxytriol and panaxydol contribute significantly to the root’s effect. These bioactive substances support the plant’s defence mechanisms and have potential skin care properties that are particularly interesting for the cosmetics industry.
Mechanism of action of polyacetylenes in cosmetics
The cosmetic significance of polyacetylenes lies primarily in three areas:
– Antimicrobial and anti-inflammatory
They act against unwanted microorganisms and can therefore be used to support the treatment of blemished skin or acne.
– Protection against oxidative stress: Due to their reactive structure, polyacetylenes bind free radicals and thus contribute to the antioxidant protection of the skin.
Due to their reactive structure, polyacetylenes bind free radicals and thus contribute to the antioxidant protection of the skin.
– Regeneration-promoting: they can promote skin regeneration.
Some polyacetylenes have a stimulating effect on cell regeneration. This is relevant for anti-ageing concepts and skin renewal.
Important polyacetylenes and their cosmetic effects
The most important known representatives of this class of substances include falcarinol and falcarindiol, which are found in carrots and parsnips. Both exhibit antimicrobial and antioxidant effects that are particularly interesting for skin care formulations against skin impurities.
Also relevant are panaxynol, panaxytriol and panaxydol from ginseng. These polyacetylenes promote skin regeneration, have an antioxidant effect and strengthen the skin barrier – ideal properties for anti-ageing products and revitalising formulations.
Oenanthotoxin from saffron water fennel is also a polyacetylene.
However, it is a highly bioactive and neurotoxic compound that is not used in cosmetics, but serves as inspiration for research into how potent this class of substances can be.
Product ideas in skin care
The special effect of polyacetylenes makes them attractive for various product categories:
– Face creams against skin impurities: Thanks to their antimicrobial properties, polyacetylenes can help reduce pimples.
– Anti-ageing serums: Due to their antioxidant and regenerative effects, they are an ideal ingredient in modern anti-wrinkle products.
– Care oils and lotions: Plant oils rich in polyacetylenes are suitable for soothing skin care formulations.
– Masks and treatments: For intensive applications that relieve the skin of oxidative stress and strengthen its natural resistance.
Conclusion: Polyacetylenes as a building block for the future of cosmetics
Polyacetylenes are highly interesting bioactive molecules that offer a wide range of benefits for skin care, from antimicrobial and antioxidant to regenerative effects.
They open up innovative possibilities for the development of modern skin care products. Please feel free to contact us.
We develop innovative products with bioactive ingredients such as polyacetylenes that are perfectly tailored to the needs of modern skin care. Alternatively, you can get started right away: Our partner, Tojo Cosmetics GmbH, offers a wide range of private label products that are available directly for the market.