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Longevity through cosmetics – the future of skin health

Longevity, with cosmetics – the future of skin health

The term ‘longevity’ refers to healthy and active ageing and is becoming increasingly important in modern skin medicine. The aim is to maintain cell function and regenerative capacity in the long term, thereby slowing down the ageing process at a cellular level. Today, longevity through cosmetics describes not only how long we live, but above all how healthy and resilient our skin is as we age. For the skin, this means that cell vitality, functionality and regenerative power should be preserved even in biological old age.

Our skin is a complex organ that combines protection, communication and aesthetics. With age, collagen content decreases, cell division slows down and oxidative damage increases. As a result, classic anti-ageing measures are increasingly being replaced by holistic well-ageing concepts that focus on the concept of longevity through cosmetics.

Four classes of active ingredients for skin longevity through cosmetics

  1. Proteins: structural building blocks

They stabilise the skin’s framework, promote cell communication and wound healing. Barrier function would be support by modulate the immune system and form a basis for regeneration – crucial for skin longevity through cosmetics.

  1. Peptides: precise signal transmitters

They stimulate collagen synthesis, support cell proliferation and have a regenerative effect. Some peptides also promote antioxidant, anti-inflammatory or antimicrobial processes. They are rightly a key factor in modern longevity strategies.

  1. Polynucleotides – natural repair aids

Polynucleotides activate DNA repair mechanisms and promote tissue regeneration. Studies have shown improvements in elasticity, hydration and wrinkles. Due to their biocompatible structure, they are a central tool for longevity-oriented skin care.

  1. Exosomes – the cell-free revolution

Exosomes transport biological signals and promote regeneration, collagen formation and barrier function. They can reduce oxidative stress and have a positive effect on UV damage, pigmentation disorders and scars. This makes them a highly innovative building block for longevity through cosmetic concepts.

Complementary approaches to longevity in the skin

In addition to the four core active ingredients, other approaches are coming to the fore:

– NAD+ precursors such as niacinamide or NMN strengthen cellular energy production.

– Ectoine protects against environmental stressors and stabilises the skin barrier.

– Mini-proteins and biotech peptides open up new possibilities in personalised skin care strategies.

All these substances help to keep the skin resilient in the long term and consistently implement the principles of longevity through cosmetics.

Product ideas with longevity ingredients

– Face serum with peptide complex and polynucleotides à For intensive regeneration, collagen build-up and smoother skin.

– Day cream with NAD+ precursor and exosomes: Supports energy production, strengthens the skin barrier and reduces oxidative stress à supports energy production, strengthens the skin barrier and reduces oxidative stress.

– Booster ampoules with ectoine and proteins à for immediate protection against environmental stress and sustainable longevity through cosmetic effects.

– Eye care with bioactive peptides and polynucleotides à Targets wrinkles and signs of fatigue.

Conclusion

Today, the term ‘longevity through cosmetics’ stands not only for a long life, but also for the mission of ageing as healthily and vitally as possible – which is also visible in the skin. Innovative active ingredients such as proteins, peptides, polynucleotides, exosomes and NAD+ precursors open up completely new possibilities for promoting skin health at a deep level.

Cosmacon develops tailor-made longevity cosmetic products for you that meet the highest standards of effectiveness and innovation.

With Tojo Cosmetics, you also have immediately available private label products for fast market entry.

Contact us – we will accompany you from the initial idea to the finished product!

Literature

  • Wyles S, Mehta R, Mannick J, Day D.Skin Longevity mittels Kosmetik : A paradigm shift in aesthetics. J Cosmet Dermatol. 2024;23:2814-2815. DOI-Link
  • Solano F.Metabolism and Functions of Amino Acids in the Skin. Adv Exp Med Biol. 2020;1265. DOI-Link
  • Errante F, Ledwoń P, Latajka R, Rovero P, Papini AM.Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy. Front Chem. 2020;8:572923. DOI-Link
  • Topouzidou N, Miliotou AN, Nodaraki D et al.Synthetic Acetyl Hexapeptide in E-Cadherin Activation for Tissue Rejuvenation. Cosmetics. 2025;12(2):48. DOI-Link
  • Rubegni P, De Aloe G, Mazzatenta C, Cattarini L, Fimiani M.Clinical evaluation of the trophic effect of PDRN. Curr Med Res Opin. 2001;17:128–131. DOI-Link
  • Yi K-H, Park M-S, Ree Y-S, Kim HM.Review on Skin Boosters. Korean Assoc Laser Dermatol Trichology. 2023;4:6. Link
  • Lee KWA, Chan KWL, Lee A et al.Polynucleotides in Aesthetic Medicine. Int J Mol Sci. 2024;25:8224. DOI-Link
  • Deng M, Yu TZ, Li D et al.Extracellular vesicles protect dermal fibroblasts from UV-induced photoaging in vitro.Photochem Photobiol Sci. 2020;19(3):406–414. DOI-Link
  • Vyas KS, Kaufman J, Munavalli GS et al.Exosomes: The Latest in Regenerative Aesthetics. Regen Med. 2023;18(2):181-194. DOI-Link