Quintup MB

1. June 2026
Pipette with serum on a beige background

Quintup MB – Revolutionary Peptide Active Ingredient for Firm, Youthful Skin

Quintup MB is a modern cosmetic active ingredient based on the latest peptide technology. It was developed to specifically target signs of skin aging such as wrinkles, moisture loss, and loss of elasticity. According to recent studies, Quintup MB has clinically proven efficacy in reducing so-called “barcode wrinkles” (vertical lip lines) and lines on the neck.

 

Chemical Composition and INCI Declaration

INCI Name:

Quintup MB: Glycerin, Water, Palmitoyl Pentapeptide-4

Quintup CC MB (oil-dispersible variant): Pentaerythrityl Tetraisostearate, Caprylic/Capric Triglyceride, Stearalkonium Hectorite, Propylene Carbonate, Palmitoyl Pentapeptide-4

This composition shows that Quintup MB is available in two variants—water-soluble and oil-soluble. This allows the active ingredient to be flexibly integrated into various cosmetic formulations, ranging from light serums to rich creams and oils.

 

Physicochemical Properties of Quintup MB

Appearance: Clear to slightly opalescent liquid

Solubility: Water-soluble (MB) / oil-dispersible (CC MB)

pH range (recommended): 4.5 – 6.5

Recommended dosage: 1.0 – 3.0%

Storage temperature: 15 – 25 °C, protected from light

Compatibility: Stable in emulsions, gels, serums

Microbiological stability: Enhanced by glycerin base

Formulation types: O/W emulsions, hydrogels, lotions, anti-aging concentrates

 

Mechanism of action and scientific findings

Quintup MB is a palmitoyl pentapeptide-4 derivative that specifically stimulates the production of collagen types I and IV in the skin. These peptides are signaling molecules that stimulate fibroblasts to produce new structural proteins—a key process for smooth, firm, and youthful-looking skin.

Additionally, Quintup MB protects collagen structures from stress hormones (e.g., cortisol) and UVA-induced degradation, making it a comprehensive anti-aging ingredient.

 

Efficacy Results and Recommended Concentration

Clinical and in vitro studies on Quintup MB and Quintup CC-MB impressively demonstrate the effectiveness of this multifunctional peptide ingredient in promoting and protecting skin structure. Significant activity at the cellular level is evident even at low concentrations:

  • Collagen gene expression: At a concentration of 5–10 ppm, Quintup MB stimulates the expression of genes for collagen types I & IV, fibronectin, and TGF-β1 in a dose-dependent manner. This effectively activates the skin’s natural collagen synthesis.
  • Stimulation of collagen synthesis: At a concentration of just 5 ppm, Quintup MB increases the production of collagen types I by up to 43%. This leads to a noticeable improvement in skin structure and firmness.
  • Protection against stress-induced collagen breakdown: At 10 ppm, Quintup MB was able to restore 77% of collagen production damaged by cortisol. Thus, the active ingredient offers highly effective protection against hormonally induced skin aging.
  • Protection against photoaging: At 10 ppm, Quintup MB has been shown to restore 46% of collagen production damaged by UVA radiation. Thus, the active ingredient effectively protects the skin against light-induced aging.
  • Anti-wrinkle effect: In a clinical study using 5% Quintup MB, a significant reduction in so-called barcode wrinkles (vertical lip lines) was observed. The skin appears visibly smoother, firmer, and more even.

These results demonstrate that Quintup MB exhibits impressive biological activity even at very low concentrations. Thanks to its dual protective and stimulating effects, the active ingredient is particularly suitable for premium anti-aging formulations aimed at visible skin rejuvenation and strengthening of the dermal matrix.

 

Benefits of Quintup MB

Quintup MB offers a range of remarkable benefits for cosmetic formulations:

  • Clinically proven efficacy: Significantly reduces fine lines, wrinkles, and neck wrinkles.
  • Multifunctional approach: Stimulates collagen production while simultaneously protecting against harmful environmental factors.
  • Flexibility: Can be used in water- or oil-based formulations.
  • Pleasant skin feel: No sticky or greasy sensation.
  • Compatibility: Stable in a wide variety of cosmetic systems.
  • Anti-stress protection: Protects collagen structures from hormone-induced stress.

 

Disadvantages of Quintup MB

Despite its compelling advantages, Quintup MB also has some considerations that should be taken into account during formulation:

  • Cost-intensive: As a high-end peptide, the price is above the average for conventional anti-aging raw materials.
  • Stability sensitivity: The peptide structure can be damaged by extreme pH levels or high temperatures.
  • Light sensitivity: Products should be packaged in light-protected containers.
  • Usage concentration: Overdosing can lead to instability in the emulsion.

 

Applications in Cosmetics

Quintup MB is ideal for all applications focused on skin rejuvenation, regeneration, and protection.

Recommended product ideas:

  • Anti-aging serums: For the face, neck, and décolleté with 2% Quintup MB.
  • Luxurious day and night creams: Combination with hyaluronic acid or ceramides.
  • Lip care with anti-wrinkle effect: For combating “barcode” wrinkles above the upper lip.
  • Neck and décolleté gels: Firming formulations with a light texture.
  • After-sun care products: Protection against UVA-induced collagen breakdown.
  • BB and CC creams: For firmer skin and improved tone.

 

Combination options with other active ingredients

For maximum effectiveness, Quintup MB can be excellently combined with other anti-aging substances, e.g.:

  • Niacinamide: Supports the skin’s barrier function and enhances radiance.
  • Vitamin C (Ascorbyl Glucoside): Further promotes collagen synthesis.
  • Hyaluronic acid: Improves skin hydration and smoothness.
  • Retinol (mild formulation): Regenerates cells and enhances the peptide effect.
  • Squalane: Supports lipid balance and skin suppleness.

 

Formulation Guidelines

  • pH Value: Optimal between 5.0 and 6.0
  • Temperature: Quintup MB should be incorporated during the cooling phase (< 40 °C)
  • Compatibility: Non-ionic and cationic systems are possible
  • Preservation: No additional preservation necessary (glycerin base has a mild antimicrobial effect)

 

Summary

Quintup MB is an innovative, clinically tested anti-aging active ingredient that visibly rejuvenates the skin through targeted stimulation of collagen I and IV and protection against stress- and UVA-induced degradation. Its high efficacy at low concentrations, combined with formulation flexibility, makes it a valuable component of modern cosmetic formulations.

Cosmacon GmbH supports brands in developing customized, highly effective cosmetic products based on Quintup MB—from premium serums to sustainable skincare concepts. With deep expertise in formulation, efficacy evaluation, and brand development, Cosmacon is your partner for innovative skincare concepts.

 

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✨ Our partner Tojo Cosmetics offers innovative, active-ingredient-rich private label products—quickly available, high-quality, and perfect for brands that want to impress with passion and quality.