Madecassoside
Madecassoside is a bioactive compound extracted from the plant Centella asiatica, commonly known as Gotu Kola. This herbal ingredient has gained popularity in the cosmetics industry due to its numerous benefits for the skin.
Introduction to Madecassoside
Madecassoside is recognised for its exceptional skin healing properties. It belongs to the triterpenoids, a class of chemical compounds known for their medicinal properties, and is increasingly used in skin care formulations.
Occurrence in nature
Botanical Name: Centella asiatica (L.) Urban
Common Names: Gotu kola, Indian pennywort, Asian pennywort
Growth Habitats: In wetlands in Asia, particularly the Indian subcontinent, Southeast Asia and in wetlands in the southeastern United States.
Description of Plant: A small, perennial herbaceous plant with kidney-shaped leaves and small pink or white flowers.
Harvest Time: Due to its perennial nature, it can generally be harvested year-round.
Flowering time: Late spring to early summer.
Growing conditions: Prefers damp, swampy locations.
Life expectancy of the plant: As a perennial, it can live for several years under optimal conditions.
Production methods
Madecassoside is extracted from the leaves and stems of Centella asiatica. The extraction process is typically by solvent extraction, which is said to maintain the purity and potency of the compound.
Benefits and concerns
- Promotes skin healing and regeneration.
- Exhibits anti-inflammatory properties and reduces skin irritation and redness.
- Provides antioxidant benefits, protecting the skin against environmental stressors.
- Promotes collagen production, contributing to skin firmness and elasticity.
- Concentration needs to be well balanced in cosmetic formulations to avoid potential skin sensitivity.
- Limited natural resources may affect sustainable sourcing.
Use in cosmetic products
Skin repair creams: For its wound healing and regenerative properties.
Anti-aging serums: Due to its collagen-boosting effect.
Formulations for sensitive skin: Helps to sooth and calm irritated skin.
Other daily applications: Madecassoside is also used in traditional medicine for its therapeutic properties in wound healing and the treatment of various skin diseases.
Chemical and physical data
Appearance: White to pale yellow powder.
Molecular formula: C48H78O20
Physical state: Solid at room temperature.
Melting point: Approximately 230-250°C.
Solubility: Soluble in certain organic solvents, slightly soluble in water.
INCI Name: Madecassoside
Alternative Names: Centella asiatica extract
Summary
Madecassoside’s potent skin healing and anti-inflammatory properties make it an extremely valuable ingredient when developing skin care products, especially for anti-aging and sensitive skin formulations. We can help you to developinnovative and effective cosmetic products that meet the needs of a growing market looking for natural and effective skin care solutions. The use of madecassoside is in line with the trend towards plant-based ingredients in cosmetics and offers potential for strengthening your brand and satisfying your customers.
Literature:
Therapeutic properties and pharmacological activities of asiaticoside and madecassoside: A review.
Bandopadhyay S, Mandal S, Ghorai M, Jha NK, Kumar M, Radha, Ghosh A, Proćków J, Pérez de la Lastra JM, Dey A.J Cell Mol Med. 2023 Mar;27(5):593-608
Lu W, Luo D, Chen D, Zhang S, Chen X, Zhou H, Liu Q, Chen S, Liu W.Molecules. 2023 Jul 7;28(13):5275
Kunjumon R, Johnson AJ, Sukumaryamma Remadevi RK, Baby S.Sci Rep. 2022 May 17;12(1):8177.
Thong-On W, Pathomwichaiwat T, Boonsith S, Koo-Amornpattana W, Prathanturarug S.Sci Rep. 2021 Nov 11;11(1):22026.
Development of Hairy Root Cultures for Biomass and Triterpenoid Production in Centella asiatica.
Baek S, Han JE, Ho TT, Park SY.Plants (Basel). 2022 Jan 6;11(2):148