{"id":19851,"date":"2026-07-20T06:00:11","date_gmt":"2026-07-20T05:00:11","guid":{"rendered":"https:\/\/www.cosmacon.de\/?p=19851"},"modified":"2026-05-03T11:01:20","modified_gmt":"2026-05-03T10:01:20","slug":"oleuropein","status":"publish","type":"post","link":"https:\/\/www.cosmacon.de\/en\/oleuropein\/","title":{"rendered":"Oleuropein"},"content":{"rendered":"<h2>Oleuropein: A Natural Shield for Skin and Health\u2014and a Versatile Active Ingredient in Modern Cosmetics<\/h2>\n<h3>Introduction: What Is Oleuropein?<\/h3>\n<p>Oleuropein is a phytochemical, more specifically a polyphenol, found primarily in the leaves and fruits of the olive tree (Olea europaea). The olive tree, often referred to as the \u201ctree of life,\u201d is an ancient cultivated plant that has been used in the Mediterranean region for thousands of years. In addition to its importance for nutrition and health, oleuropein is now also coming into focus in cosmetic research\u2014with promising results.<\/p>\n<p>&nbsp;<\/p>\n<h2>Occurrence in Nature<\/h2>\n<p>Oleuropein is found primarily in the leaves of the olive tree, but also in the skin and flesh of olives. The evergreen olive tree thrives in warm, sunny climates such as Southern Europe, North Africa, the Middle East, as well as parts of South America and Australia. It can grow up to 10 meters tall and reach a remarkable age of several hundred years. The flowering season begins in spring, and the olive harvest traditionally takes place in autumn.<\/p>\n<p>&nbsp;<\/p>\n<h2>Extraction and Production<\/h2>\n<p>Oleuropein is obtained through extraction from dried olive leaves. Modern extraction methods such as ultrasonic extraction or CO\u2082 extraction enable the gentle isolation of active ingredients with high purity. Standardized oleuropein powder typically contains at least 80% oleuropein and is available as a hygroscopic, pale yellow crystalline powder.<\/p>\n<p>&nbsp;<\/p>\n<h2>Physicochemical Properties of Oleuropein<\/h2>\n<p><b>INCI Name:<\/b> Olea Europaea (Olive) Leaf Extract<\/p>\n<p><b>CAS Number:<\/b> 8001-25-0<\/p>\n<p><b>Molecular Formula:<\/b> C25H32O13<\/p>\n<p><b>Appearance:<\/b> Pale yellow crystalline powder<\/p>\n<p><b>Physical State:<\/b> Solid<\/p>\n<p><b>Melting point:<\/b> approx. 165\u2013170 \u00b0C<\/p>\n<p><b>Solubility:<\/b> Moderately soluble in water, more soluble in ethanol<\/p>\n<p><b>Active ingredient content:<\/b> \u2265 80% oleuropein<\/p>\n<p><b>Recommended usage concentration:<\/b> 0.5\u20131% in cosmetic formulations<\/p>\n<p>&nbsp;<\/p>\n<h2>Efficacy and recommended usage concentration<\/h2>\n<p>Studies demonstrate that oleuropein exhibits antioxidant, antimicrobial, and anti-inflammatory properties at concentrations of 0.5% to 1% in cosmetic formulations. In vitro studies show that oleuropein is even more effective than vitamin E at scavenging free radicals and reducing oxidative stress. The EC\u2085\u2080 values are below 10 \u00b5M\u2014an indication of its high efficacy at low doses.<\/p>\n<h3>Study results on efficacy<\/h3>\n<ul>\n<li><b>Antioxidant performance:<\/b> In a direct comparison with Trolox and vitamin C, oleuropein performed excellently in neutralizing free radicals (e.g., superoxide anions, DPPH radicals).<\/li>\n<li><b>Anti-inflammatory effect:<\/b> In preclinical efficacy models, a 0.5 mg application per skin area reduced inflammation by over 30%\u2014comparable to dexamethasone.<\/li>\n<li><b>Antimicrobial effect:<\/b> As little as 0.1% oleuropein slowed the growth of Staphylococcus aureus; at 0.4% and above, growth was completely inhibited.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2>Benefits of Oleuropein in Cosmetics<\/h2>\n<ul>\n<li><b>Antioxidant:<\/b> Protects the skin from free radicals, prevents premature skin aging.<\/li>\n<li><b>Anti-inflammatory:<\/b> Helps with irritated or inflamed skin, including acne and eczema.<\/li>\n<li><b>Antimicrobial:<\/b> Inhibits the growth of bacteria and fungi\u2014ideal for products targeting skin imperfections.<\/li>\n<li><b>Anti-aging:<\/b> Supports cell renewal and improves skin texture.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2>Disadvantages and Challenges<\/h2>\n<ul>\n<li><b>Taste\/Odor:<\/b> In food, oleuropein has a bitter taste, which can be a disadvantage for oral products.<\/li>\n<li><b>Stability:<\/b> In cosmetic formulations, stability must be ensured when exposed to light and heat. Suitable packaging (e.g., airless dispensers) is necessary.<\/li>\n<li><b>Price:<\/b> High-purity oleuropein extracts are more expensive than simple plant extracts.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2>Application ideas for cosmetic products with oleuropein<\/h2>\n<p>Thanks to its versatility, oleuropein is an ideal active ingredient for various cosmetic applications:<\/p>\n<ul>\n<li><b>Anti-aging cream:<\/b> In combination with hyaluronic acid, oleuropein has antioxidant and cell-protective effects.<\/li>\n<li><b>Serum for sensitive skin:<\/b> Ideal for redness, rosacea, or post-inflammatory hyperpigmentation.<\/li>\n<li><b>Face mask for blemishes:<\/b> When combined with clay and zinc, it regulates sebum production.<\/li>\n<li><b>After-sun lotion:<\/b> Protects the skin from oxidative stress caused by UV radiation.<\/li>\n<li><b>Deodorant spray:<\/b> Antibacterial action reduces odor formation.<\/li>\n<li><b>Lip care:<\/b> As a protective, regenerating active ingredient for chapped lips.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2>Summary<\/h2>\n<p>Oleuropein is a highly effective, plant-based bioactive ingredient with great potential for modern skincare. Its antioxidant, antimicrobial, and anti-inflammatory properties make it a versatile active ingredient that is ideal for sensitive, blemish-prone, or mature skin. Particularly noteworthy is its high efficacy even at low dosages, as well as its good skin tolerance.<\/p>\n<p>&nbsp;<\/p>\n<h3>Cosmacon GmbH \u2013 Your Partner for Innovative Active Ingredient Cosmetics<\/h3>\n<p>Cosmacon GmbH supports you in developing customized cosmetic products with oleuropein. Whether it\u2019s an anti-aging serum, detox cream, or skin-soothing facial care\u2014we work with you to design modern, effective, and brand-strengthening formulations. Benefit from our experience in active ingredient cosmetics and take your brand to the next level. Let yourself be inspired by the power of the \u201cTree of Life\u201d!<\/p>\n<p>Would you like to develop innovative products with oleuropein? <a href=\"https:\/\/www.cosmacon.de\/en\/contact\/enquiry\/\" target=\"_blank\" rel=\"noopener\">Contact Cosmacon \u2013 we\u2019d be happy to advise you<\/a>.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>When speed is of the essence:<\/strong><\/p>\n<p>\u2728 Our partner <a href=\"https:\/\/www.tojocosmetics.de\/produkte\/\" target=\"_blank\" rel=\"noopener\">Tojo Cosmetics<\/a> offers innovative, active-ingredient-rich private label products\u2014quickly available, high-quality, and perfect for brands that want to impress with passion and quality.<\/p>\n<p>&nbsp;<\/p>\n<h2>References:<\/h2>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39845787\/\" target=\"_blank\" rel=\"noopener\">Anti-inflammatory and antioxidant properties of <b>oleuropein<\/b> in human keratinocytes characterized by bottom-up proteomics.<\/a><\/p>\n<p>Li H, Deng N, Yang J, Zhao Y, Jin X, Cai A, Seeram NP, Ma H, Li D, Yang H, Liu C. Front Pharmacol. 2025 Jan 8;15:1496078.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36871904\/\" target=\"_blank\" rel=\"noopener\">Co-delivery of <b>oleuropein<\/b> and lentisk oil in phospholipid vesicles as an effective approach to modulate oxidative stress, cytokine secretion, and promote <b>skin<\/b> regeneration.<\/a><\/p>\n<p>Sklenarova R, Allaw M, Perra M, Castangia I, Frankova J, Luis Pedraz J, Letizia Manca M, Manconi M. Eur J Pharm Biopharm. Apr 2023;185:126-136.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37298828\/\" target=\"_blank\" rel=\"noopener\"><b>Oleuropein<\/b>-Rich Gellan Gum\/Alginate Films as Innovative Treatments against Photo-Induced <b>Skin<\/b> Aging.<\/a><\/p>\n<p>Busto F, Licini C, Luccarini A, Damiani E, Mattioli-Belmonte M, Cometa S, De Giglio E. Molecules. 2023 May 25;28(11):4352.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Oleuropein: A Natural Shield for Skin and Health\u2014and a Versatile Active Ingredient in Modern Cosmetics Introduction: What Is Oleuropein? Oleuropein is a phytochemical, more specifically a polyphenol, found primarily in the leaves and fruits of the olive tree (Olea europaea). The olive tree, often referred to as the \u201ctree of life,\u201d is an ancient cultivated&hellip;<\/p>\n","protected":false},"author":2,"featured_media":19855,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-19851","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-allgemein-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Oleuropein: Benefits &amp; Uses in Skincare<\/title>\n<meta name=\"description\" content=\"Oleuropein from the olive tree: antioxidant, anti-inflammatory, and ideal for modern skincare and anti-aging.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cosmacon.de\/en\/oleuropein\/\" \/>\n<meta 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