{"id":19121,"date":"2026-02-09T06:00:54","date_gmt":"2026-02-09T05:00:54","guid":{"rendered":"https:\/\/www.cosmacon.de\/?p=19121"},"modified":"2025-11-11T12:12:02","modified_gmt":"2025-11-11T11:12:02","slug":"dermosoft-gpt-mb-microbiome-friendly-preservation-power","status":"publish","type":"post","link":"https:\/\/www.cosmacon.de\/en\/dermosoft-gpt-mb-microbiome-friendly-preservation-power\/","title":{"rendered":"Dermosoft GPT MB"},"content":{"rendered":"<h2 style=\"font-weight: 400;\">Dermosoft\u00ae GPT MB \u2013 Natural intelligence for modern cosmetic products<\/h2>\n<p style=\"font-weight: 400;\">At a time when consumers are increasingly looking for natural ingredients and microbiome-friendly formulations, dermosoft\u00ae GPT MB is sending a strong signal about the future of skin care. Developed by Evonik Dr. Straetmans GmbH, this innovative active ingredient combines high efficacy, versatility, and sustainable properties. In this article, we highlight the strengths and weaknesses of dermosoft\u00ae GPT MB, present its physicochemical characteristics, analyze study results, and outline application ideas for cosmetic products.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2 style=\"font-weight: 400;\">What is dermosoft\u00ae GPT MB?<\/h2>\n<p style=\"font-weight: 400;\">dermosoft\u00ae GPT MB is a multifunctional, natural active ingredient based on glyceryl sesquipelargonate. It serves as a cosmetic wetting agent enhancer with additional antimicrobial properties and can be used in a variety of ways\u2014in emulsions as well as in aqueous and surfactant-based systems.<\/p>\n<p style=\"font-weight: 400;\">The aim is to solve formulation and microbiological challenges without compromising skin compatibility or environmental friendliness. The active ingredient is completely natural, 100% biodegradable, vegan, and free from animal ingredients.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2 style=\"font-weight: 400;\">Physicochemical characteristics of dermosoft\u00ae GPT MB<\/h2>\n<p style=\"font-weight: 400;\"><strong>INCI:<\/strong>\u00a0Glyceryl Sesquipelargonate<\/p>\n<p style=\"font-weight: 400;\"><strong>Appearance:<\/strong>\u00a0Clear, slightly yellowish liquid to paste<\/p>\n<p style=\"font-weight: 400;\"><strong>Odor:<\/strong>\u00a0Characteristic, pleasant<\/p>\n<p style=\"font-weight: 400;\"><strong>Natural origin:<\/strong>\u00a0100% (Natural Origin Index = 1.0, ISO 16128)<\/p>\n<p style=\"font-weight: 400;\"><strong>Biodegradability:<\/strong>\u00a0Complete, readily biodegradable<\/p>\n<p style=\"font-weight: 400;\"><strong>pH range:<\/strong>\u00a04.0\u20137.0<\/p>\n<p style=\"font-weight: 400;\"><strong>Solubility:<\/strong>\u00a0Highly soluble in ethanol, propylene glycol, butylene glycol, dermofeel\u00ae TEC eco<\/p>\n<p style=\"font-weight: 400;\"><strong>Water solubility:<\/strong>\u00a0Low, therefore solubilization required<\/p>\n<p style=\"font-weight: 400;\"><strong>Processing temperature:<\/strong>\u00a0Up to max. 80 \u00b0C, can be processed cold<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2 style=\"font-weight: 400;\">Antimicrobial efficacy &amp; recommended use concentration<\/h2>\n<p style=\"font-weight: 400;\">dermosoft\u00ae GPT MB exhibits a broad antimicrobial spectrum against Gram-positive and Gram-negative bacteria and yeasts. An additional combination is required against molds.<\/p>\n<p style=\"font-weight: 400;\"><strong>Recommended concentrations:<\/strong><\/p>\n<ul>\n<li style=\"font-weight: 400;\">General applications (emulsions, aqueous systems, surfactant systems): 0.3\u20131.0%<\/li>\n<li style=\"font-weight: 400;\">Deodorant cream: 0.3\u20130.6%<\/li>\n<li style=\"font-weight: 400;\">Baby products (except diaper area): 0.2\u20130.4%<\/li>\n<li style=\"font-weight: 400;\">Oral care: 0.1\u20130.3%<\/li>\n<\/ul>\n<p style=\"font-weight: 400;\">For complete microbial control, combination with organic acids or aromatic alcohols is recommended.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2 style=\"font-weight: 400;\">Study results on microbiome friendliness<\/h2>\n<p style=\"font-weight: 400;\">A key strength of dermosoft\u00ae GPT MB is its confirmed skin friendliness. In an in vivo study with Asian skin, microbial diversity was examined using qPCR measurements.<\/p>\n<p style=\"font-weight: 400;\"><strong>Results:<\/strong><\/p>\n<ul>\n<li style=\"font-weight: 400;\">dermosoft\u00ae GPT MB reduced the total bacterial count only slightly compared to the control group.<\/li>\n<li style=\"font-weight: 400;\">In contrast to phenoxyethanol, which significantly reduced microbial life, microbiological diversity was maintained.<\/li>\n<li style=\"font-weight: 400;\">Conclusion: dermosoft\u00ae GPT MB respects the natural skin microbiome.<\/li>\n<\/ul>\n<p style=\"font-weight: 400;\">This makes the active ingredient particularly attractive for sensitive skin, baby, and intimate care products.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2 style=\"font-weight: 400;\">Co-emulsifying effect<\/h2>\n<p style=\"font-weight: 400;\">Another advantage of dermosoft\u00ae GPT MB is its co-emulsifying effect, which leads to faster and more stable emulsion formation. Even with an addition of only 1%, tests showed a significantly faster O\/W emulsion at 80 \u00b0C within 30 seconds. The resulting emulsion was whiter and less translucent compared to the control group\u2014an indicator of finer droplet size and better emulsion stability.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2 style=\"font-weight: 400;\">Advantages of dermosoft\u00ae GPT MB<\/h2>\n<ul>\n<li style=\"font-weight: 400;\">100% natural origin\u2014ideal for clean beauty concepts.<\/li>\n<li style=\"font-weight: 400;\">Broad antimicrobial spectrum without classic preservatives.<\/li>\n<li style=\"font-weight: 400;\">Microbiome-friendly, proven by in vivo studies.<\/li>\n<li style=\"font-weight: 400;\">Versatile: emulsions, surfactant formulations, hydroalcoholic solutions.<\/li>\n<li style=\"font-weight: 400;\">Biodegradable and environmentally friendly.<\/li>\n<li style=\"font-weight: 400;\">Can be processed at low temperatures, which saves energy.<\/li>\n<li style=\"font-weight: 400;\">Co-emulsifying and odor-masking properties.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2 style=\"font-weight: 400;\">Disadvantages and challenges<\/h2>\n<ul>\n<li style=\"font-weight: 400;\">Low water solubility\u2014solubilizers are required for transparent aqueous systems.<\/li>\n<li style=\"font-weight: 400;\">Tendency to crystallize at room temperature\u2014product must be heated to 40\u201350 \u00b0C before use.<\/li>\n<li style=\"font-weight: 400;\">Not effective against mold on its own \u2013 must be combined with fungicidal additives.<\/li>\n<li style=\"font-weight: 400;\">Emulsion viscosity may be affected depending on the emulsifier system \u2013 adjustment required.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2 style=\"font-weight: 400;\">Ideas for cosmetic product concepts<\/h2>\n<p style=\"font-weight: 400;\"><strong>Mild micellar cleansing water<\/strong><\/p>\n<p style=\"font-weight: 400;\">Ideal for sensitive skin, formulated with dermasoft\u00ae GPT MB + Verstatil\u00ae BL for gentle but effective cleansing without irritation.<\/p>\n<p style=\"font-weight: 400;\"><strong>Gentle deodorant cream with long-lasting protection<\/strong><\/p>\n<p style=\"font-weight: 400;\">Combination of dermasoft\u00ae GPT MB with Heptyl MB: gentle on underarm skin, protects against unpleasant odors.<\/p>\n<p style=\"font-weight: 400;\"><strong>Antibacterial baby lotion<\/strong><\/p>\n<p style=\"font-weight: 400;\">Perfectly dosed with 0.3% dermasoft\u00ae GPT MB: protects sensitive baby skin without disturbing the microbiome.<\/p>\n<p style=\"font-weight: 400;\"><strong>Hydrating day cream with pigment boost<\/strong><\/p>\n<p style=\"font-weight: 400;\">Co-emulsifier effect improves texture, even distribution of color pigments through optimized wetting.<\/p>\n<p style=\"font-weight: 400;\"><strong>After-sun care gel<\/strong><\/p>\n<p style=\"font-weight: 400;\">Antimicrobial, soothing, and stable\u2014ideal after sunbathing.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2 style=\"font-weight: 400;\">Conclusion<\/h2>\n<p style=\"font-weight: 400;\">dermosoft\u00ae GPT MB is much more than just a preservative booster\u2014it is an intelligent, natural active ingredient that meets the requirements of modern skin care products: microbiome-friendly, environmentally compatible, versatile, and efficient. With a wide range of applications \u2013 from emulsions and micellar water to deodorant creams \u2013 it offers formulators the flexibility they need for innovative product concepts.<\/p>\n<p style=\"font-weight: 400;\">Those who work with this active ingredient are not only choosing effectiveness, but also responsibility towards the skin, people, and the environment.<\/p>\n<p>&nbsp;<\/p>\n<p style=\"font-weight: 400;\"><strong>Would you like to use dermosoft\u00ae GPT MB in your products?<\/strong><\/p>\n<p style=\"font-weight: 400;\">Cosmacon GmbH is your development partner when it comes to tailor-made, nature-based cosmetic solutions. With years of experience, access to the latest active ingredients, and in-depth formulation expertise, Cosmacon develops innovative products that differentiate your brand.<\/p>\n<p style=\"font-weight: 400;\"><a href=\"https:\/\/www.cosmacon.de\/en\/contact\/enquiry\/\" target=\"_blank\" rel=\"noopener\">Contact us<\/a> and start your next successful formulation with dermosoft\u00ae GPT MB.<\/p>\n<p>&nbsp;<\/p>\n<p style=\"font-weight: 400;\">\n<p><strong>When products are needed quickly:<\/strong><\/p>\n<p>\u2728 Our partner <a href=\"https:\/\/www.tojocosmetics.de\/en\/produkte\/\" target=\"_blank\" rel=\"noopener\">Tojo Cosmetics<\/a> offers innovative, active ingredient-rich private label products \u2013 quickly available, high quality and perfect for brands that want to impress with passion and quality.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dermosoft\u00ae GPT MB \u2013 Natural intelligence for modern cosmetic products At a time when consumers are increasingly looking for natural ingredients and microbiome-friendly formulations, dermosoft\u00ae GPT MB is sending a strong signal about the future of skin care. Developed by Evonik Dr. Straetmans GmbH, this innovative active ingredient combines high efficacy, versatility, and sustainable properties.&hellip;<\/p>\n","protected":false},"author":2,"featured_media":19123,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-19121","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-allgemein-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>dermosoft\u00ae GPT MB \u2013 Microbiome-Friendly Preservation Power<\/title>\n<meta name=\"description\" content=\"Natural and effective: dermosoft\u00ae GPT MB protects formulations, supports skin balance, and aligns with clean beauty trends.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" 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