{"id":13454,"date":"2023-04-29T21:01:11","date_gmt":"2023-04-29T20:01:11","guid":{"rendered":"https:\/\/www.cosmacon.de\/?post_type=encyclopedia&#038;p=13454"},"modified":"2023-04-29T21:01:48","modified_gmt":"2023-04-29T20:01:48","slug":"squalane","status":"publish","type":"encyclopedia","link":"https:\/\/www.cosmacon.de\/en\/glossary\/squalane\/","title":{"rendered":"Squalane"},"content":{"rendered":"<p>Squalane is a highly effective plant-based skin care substance that is nowadays mainly extracted from olives. In the past, however, things were different: originally, squalane was obtained from shark liver, 80 percent of which consists of squalene (not to be confused with squalane!). Hence the name: Squalus is the Latin name for shark. But first a few words about the origin: squalene is very widespread in our nature, because it is not only found in plants and sharks, but in all higher creatures and thus also in humans. It is a very important component of skin lipids. However, when squalene is industrially hydrogenated, it becomes squalane: a liquid oil component that is resistant to oxygen, light and heat and is mainly used in emulsions as well as hair care products and bath oils.<\/p>\n<p>&nbsp;<\/p>\n<h3>Why squalane is so incredibly valuable<\/h3>\n<p>Basically, squalene is unsaturated and can oxidise. The cosmetics industry therefore uses saturated squalene, so-called squalane, which then no longer has any unsaturated double bonds and is therefore resistant to oxidation and heat. It is produced from unsaponifiable components of the press residues of classic olive oil. In order to clarify the origin from plant sources (and not from animal sources such as sharks), some manufacturers also use the term phytosqualan. Squalane is completely non-irritating and makes the skin feel extremely soft, silky, smooth and non-greasy. As a saturated hydrocarbon, squalane itself is hardly absorbed, but it has a positive influence on the absorption behaviour of cosmetics, as it improves the spreading properties of emulsions and at the same time reduces a greasy feel. Squalane is particularly suitable for sensitive, dry, brittle or flaky skin (for example, skin problems such as psoriasis and neurodermatitis). As it is extremely mild, it can also be used without hesitation in products for small children. As an oxidation-stable lipid, squalane is also excellently suited for sun protection products.<\/p>\n<p>It preserves the skin&#8217;s suppleness and protects it from moisture loss, which also improves the structure of the natural lipid film. When squalane is used in hair care products, it significantly improves the combability of the hair.<br \/>\nSqualane spreads easily on the skin and is colourless and odourless. It is an ideal base for make-up and can even be used to remove make-up. That is why it is being used in more and more cosmetic products.<br \/>\nIn some formulations, squalane is also used in somewhat higher doses as a lipid component, depending on the concept. In this case, however, it must be noted that it gives the emulsion a more fluid consistency due to its low viscosity.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Fact Sheet Squalane:<\/strong><\/p>\n<p>CAS number: 111-01-3<br \/>\nAlternative names: Hexamethyltetracosan, Cosbiol, Vitabiosol, Roban.<br \/>\nMolecular formula C30H62<br \/>\nBrief description: colourless, oily liquid<br \/>\nMelting point: minus 38 degrees Celsius<br \/>\nSolubility: insoluble in water, soluble in diethyl ether and benzene, slightly soluble in acetone and ethanol<\/p>\n<p>&nbsp;<\/p>\n<p><strong>We like to work with these raw materials containing squalane:<\/strong><\/p>\n\n<table id=\"tablepress-327\" class=\"tablepress tablepress-id-327\">\n<thead>\n<tr class=\"row-1\">\n\t<th class=\"column-1\">Tradename<\/th><th class=\"column-2\">INCI<\/th><th class=\"column-3\">Supplier<\/th><th class=\"column-4\">Remarks<\/th>\n<\/tr>\n<\/thead>\n<tbody class=\"row-striping row-hover\">\n<tr class=\"row-2\">\n\t<td class=\"column-1\">Keteol N<\/td><td class=\"column-2\">Squalane (natural)<\/td><td class=\"column-3\">Laboratories Prod'Hyg<\/td><td class=\"column-4\"><\/td>\n<\/tr>\n<tr class=\"row-3\">\n\t<td class=\"column-1\">Keteol V<\/td><td class=\"column-2\">Squalane (vegetal)<\/td><td class=\"column-3\">Laboratories Prod'Hyg<\/td><td class=\"column-4\"><\/td>\n<\/tr>\n<tr class=\"row-4\">\n\t<td class=\"column-1\">Plantasens Olive Squalane<\/td><td class=\"column-2\">Squalane<\/td><td class=\"column-3\">Clariant<\/td><td class=\"column-4\"><\/td>\n<\/tr>\n<tr class=\"row-5\">\n\t<td class=\"column-1\">Squalane , Vegetable<\/td><td class=\"column-2\">Squalane<\/td><td class=\"column-3\">Worl\u00e9e Chemie GmbH<\/td><td class=\"column-4\"><\/td>\n<\/tr>\n<tr class=\"row-6\">\n\t<td class=\"column-1\">Koboguard 5400 SQ<\/td><td class=\"column-2\">Hydrogenated Polycyclopentadiene (and) Squalane<\/td><td class=\"column-3\">Kobo Products<\/td><td class=\"column-4\"><\/td>\n<\/tr>\n<tr class=\"row-7\">\n\t<td class=\"column-1\">Emortal<\/td><td class=\"column-2\">Propanediol (and) Aqua (and) Phytosterols (and) Lecithin (and) Olea Europaea (Olive) Fruit Oil (and) Squalane (and) Hydrolyzed Pea Protein (and) Butyrospermum Parkii (Shea) Butter (and) Ceramide NP<\/td><td class=\"column-3\">Bio-Spectrum<\/td><td class=\"column-4\"><\/td>\n<\/tr>\n<tr class=\"row-8\">\n\t<td class=\"column-1\">Koplene<\/td><td class=\"column-2\">Squalene<\/td><td class=\"column-3\">Kumarorganic<\/td><td class=\"column-4\"><\/td>\n<\/tr>\n<tr class=\"row-9\">\n\t<td class=\"column-1\">Koplane<\/td><td class=\"column-2\">Squalane<\/td><td class=\"column-3\">Kumarorganic<\/td><td class=\"column-4\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<!-- #tablepress-327 from cache -->\n<p>&nbsp;<\/p>\n<h3>Conclusion: Squalane as an optimal moisture preserver<\/h3>\n<p>Cosmetic products containing squalane leave the skin feeling wonderfully silky and are ideal moisture retainers. The skin care ingredient is very well tolerated and even suitable for very dry skin and children. It is also used very effectively in sun protection and hair care products. The fact that squalane is no longer obtained from sharks, but from olives, is also very positive.<\/p>\n<p><a href=\"https:\/\/www.cosmacon.de\/en\/contact\/enquiry\/\" target=\"_blank\" rel=\"noopener\">Feel free to ask us, we will develop a great product with squalane for your brand.<\/a><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Literature<\/strong><\/p>\n<ul>\n<li>S-K Kim and F Karadeniz,Biological importance and applications of squalene and squalane, in <em>Advances in Food and Nutrition Research<\/em>, <em>vol 65<\/em>, S-K Kim, ed, Elsevier, Amsterdam, ch14 (2012) pp 223-233<\/li>\n<li>Final report on the safety assessment of squalaneand squalene, <em>Int J Toxicol<\/em> 1 37-56 (1982)<\/li>\n<li>KR Smith and DM Thiboutot,Thematic review series: Skin lipids. Sebaceous gland lipids: Friend or foe? <em>J Lipid Res <\/em>49 271-281 (2008)<\/li>\n<li>RS Greene, DT Downing, PE Pochi and JS Strauss, Anatomical variation in the amount and composition of human skin surface lipid, <em>J Invest Dermatol<\/em> 54 240-247 (1970)<\/li>\n<li>T Nikkari, PH Schreibman and EH Ahrens, Jr, In vivo studies of sterol and squalene secretion by human skin, <em>J Lipid Res<\/em> 15 563-573 (1974)<\/li>\n<li>F Bouvier, A Rahier and B Camara,Biogenesis, molecular regulation and function of plant isoprenoids, <em>Prog Lipid Res <\/em>44 357-429 (2005)<\/li>\n<li>M Spanova and G Daum,Squalene\u2014Biochemistry, molecular biology, process biotechnology and applications, <em>Eur J Lipid Sci Technol<\/em> 113 1299-1320 (2011), and references therein<\/li>\n<li>E Andre and H Canal, Contribition a l\u2019\u00e9tude des huiles d\u2019animaux marins. I. Recherches sur le squal\u00e9ne et la spinac\u00e9ne, <em>Ann ChimAppl<\/em> 7 69-112 (1927)<\/li>\n<li>M Tsujimoto, An unsaturated hydrocarbon in shark liver oil, <em>J Chem Ind Jpn<\/em>\u00a019 277-281 (1916)<\/li>\n<li>P Karrer and A Helfenstein, Synthesis of squalene,<em>HelvChim Acta<\/em>\u00a014\u00a078-85 (1931)<\/li>\n<li>S Sabetay, Five years of perhydrosqualene\u2014A revolution in cosmetics, <em>RiechstoffArom<\/em>\u00a05\u00a0274-276 (1955)<\/li>\n<li>T Nishida, Y Ninagawa, K Itoi and Y Fujita, New industrial synthesis of squalane, <em>Bull Chem Soc Jpn<\/em> 56 2805-2810 (1983)<\/li>\n<li>J Grossfeld and H Timm, A new characteristic for oliveoil, <em>Z UntersLebensm<\/em> 77\u00a0249-253 (1939)<\/li>\n<li>MT Gapor and AR Hazrina, Squalene in oils and fats, <em>Palm Oil Develop<\/em> 32 36-40 (2000)<\/li>\n<li>CA Auguet, A new source of Ssqualane, <em>Drug Cosmet Ind<\/em> 82 51-53 (1988)<\/li>\n<li>W Dickhart, The squalene contents of various oils,<em>Am J Pharm<\/em>127 359-361 (1955)<\/li>\n<li>K Taufel, H Heinisch and W Heimann, The distribution of squalenes in vegetable fats,<em>Biochem Z<\/em>\u00a0303\u00a0324-8 (1940)<\/li>\n<li>MM Storelli, E Ceci, A Storelli and GO Marcotrigiano, Polychlorinated biphenyl, heavy metal and methylmercury residues in hammerhead sharks: Contaminant status and assessment, <em>Mar Pollut Bull <\/em>46 1035-1039 (2003)<\/li>\n<li>A Gasparoli, C Mariani and MG Fedrigucci, Squalane: Differentiation between vegetable and animal origin, <em>Riv Ital Sostan Grasse<\/em> 73 293-302 (1996)<\/li>\n<li>A.Gasparoli, CMariani, ME Gaboardi, G Morchio and G Santus, About detection of animal squalene\/\u200bsqualene in vegetable products used in the cosmetic field, <em>Riv Ital Sostan Grasse<\/em> 89 4-28 (2012)<\/li>\n<li>Ruzicka. The isoprene rule and the biogenesis of terpenic compounds. <em>Experientia<\/em> 9 357-67 (1953)<\/li>\n<li>F Mantzouridou and MZ Tsimidou, Observations on squalene accumulation in <em>Saccharomyces cerevisiae<\/em> due to the manipulation of <em>HMG2<\/em> and ERG6,<em> FEMS Yeast Res<\/em> 10 699-707 (2010), and references therein<\/li>\n<li>S.S.Chandran, JT Kealey and CDReeves, Microbial production of isoprenoids,<em> Process Biochem<\/em> 46 1703-1710 (2011)<\/li>\n<li>L Zhao, W Chang, Y Xiao, HLiu and P Liu, Methylerythritol phosphate pathway of isoprenoid biosynthesis,\u00a0<em>Ann Rev Biochem<\/em> 82 497-530 (2013<\/li>\n<li><a class=\"docsum-title\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35789811\/\" data-ga-category=\"result_click\" data-ga-action=\"2\" data-ga-label=\"35789811\" data-full-article-url=\"from_term=%28squalan%29+AND+%28cosmetics%29&amp;from_filter=simsearch2.ffrft&amp;from_filter=datesearch.y_10&amp;from_exact_term=%28squalane%29+AND+%28cosmetics%29&amp;from_pos=2\" data-article-id=\"35789811\">Recent Progress in Microalgal Squalene Production and Its\u00a0<b>Cosmetic<\/b> Application. <\/a><span class=\"docsum-authors full-authors\">Yarkent \u00c7, Oncel SS.<\/span><span class=\"docsum-journal-citation full-journal-citation\">Biotechnol Bioprocess Eng. 2022;27(3):295-305<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Squalane is a highly effective plant-based skin care substance that is nowadays mainly extracted from olives. In the past, however, things were different: originally, squalane was obtained from shark liver, 80 percent of which consists of squalene (not to be confused with squalane!). Hence the name: Squalus is the Latin name for shark. But first&hellip;<\/p>\n","protected":false},"author":2,"featured_media":7987,"template":"","class_list":["post-13454","encyclopedia","type-encyclopedia","status-publish","has-post-thumbnail","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Squalane - Cosmacon<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cosmacon.de\/en\/glossary\/squalane\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Squalane - Cosmacon\" \/>\n<meta property=\"og:description\" content=\"Squalane is a highly effective plant-based skin care substance that is nowadays mainly extracted from olives. 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